• Unlocking Brain Chemistry: The Power of Dopamine, Oxytocin, Serotonin & Endorphins
    May 15 2026

    In this episode with TJ Power, the discussion delves into the impact of modern lifestyle on mental health, focusing on conditions like mild anxiety and depression. TJ Power, a neuroscientist, shares insights from his book "The Dose Effect," which explores how dopamine, oxytocin, serotonin, and endorphins can be optimised to improve well-being. The conversation covers TJ's personal journey with dopamine addiction and how he developed a protocol to rebalance brain chemistry. We also discuss the importance of evolutionary biology, the role of technology in mental health, and practical steps to enhance connection and reduce stress in today's fast-paced world.

    Discover practical strategies to optimise brain chemistry, overcome modern lifestyle disorders, and foster deeper human connection.

    Key Takeaways

    • Impact of modern lifestyle on mental health
    • Role of dopamine in motivation and addiction
    • Oxytocin and human connection
    • Serotonin's influence on body-brain health
    • Endorphins and stress relief through exercise
    • Practical strategies for neurochemical balance
    • The importance of behavioural first approaches
    • The science of shared suffering and bonding
    • Effects of technology and social media on dopamine
    • Strategies for lifestyle changes to improve mental health

    Time Stamps

    01:12 Modern Lifestyle Disorders and the Dose Effect

    02:04 TJ Power's Journey and the DOSELAB

    04:16 Research Challenges and Funding

    06:05 In-Person vs. Online Interventions

    08:02 Understanding Dopamine

    10:01 Dopamine's Role in Motivation and Anticipation

    11:58 The Impact of Modern Rewards on Dopamine

    13:54 Fast vs. Slow Dopamine

    16:05 The Consequences of Low Dopamine

    18:02 Behavioural Approaches to Mental Health

    20:00 The Importance of Action in Motivation

    21:55 Practical Challenges for Dopamine Optimization

    23:50 Phone Fasting and Digital Detox

    25:36 Dopamine and ADHD

    28:37 Understanding ADHD and Dopamine

    31:59 The Role of Oxytocin in Human Connection

    38:36 The Power of Connection in Adversity

    46:37 Cultivating Oxytocin in Daily Life

    48:43 Exploring Serotonin and Body-Brain Connection

    01:01:24 The Impact of Endorphins on Well-being

    Resources

    Website: DOSELab

    The DOSE Effect: https://geni.us/UFOm – TJ Power’s book

    LinkedIn - https://www.linkedin.com/in/tjpowerneuroscience/

    Instagram - https://www.instagram.com/tjpower/

    Website: https://tjpower.co.uk/

    Support the Podcast

    If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics.

    See omnystudio.com/listener for privacy information.

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    1 hr and 20 mins
  • An eggcellent dietary habit to keep your brain healthy and help prevent Alzheimer's Disease
    May 13 2026

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    9 mins
  • The Words You're Living By With Carly Taylor
    May 10 2026

    This week on Mojo Monday, Carly explores the power of language in shaping our experiences. She delves into the concept of relational frame theory, which suggests that our minds create connections and meaning through language, influencing how we feel about our lives.

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    5 mins
  • Choose your hard: Science-backed strategies to thrive in a difficult world, with Emeritus Professor Grant Schofield
    May 8 2026

    If you think ease and comfort are the keys to happiness, think again. This episode explores how deliberately embracing life's challenges—through movement, fasting, cold exposure, and mental resilience—can transform your health, happiness, and purpose. Grant Schofield, an esteemed researcher and author, reveals that life's true reward lies in choosing the hard path, strong in the knowledge that it leads to a more vibrant, resilient life.

    Choose your path, and in doing so, choose your future. And for those ready to take action, Grant’s new book Choose Your Hard distils these powerful principles into actionable step because the path to a better life is a deliberate choice.

    00:00 The Role of an Emeritus Professor

    02:57 The Academic Publishing Industry

    05:54 Understanding Misogi and Personal Challenges

    09:00 Fasting and Autophagy Explained

    12:01 The Science of Metabolism and Immune Function

    15:04 Psychological Aspects of Fasting

    17:58 Preparing for a Fast: Strategies and Mindset

    20:58 Physical Responses and Adaptations During Fasting

    25:51 The Role of Stress in Health

    27:28 Choosing Your Hard: Embracing Life's Challenges

    35:19 Agency and Responsibility in Health

    40:10 Movement: The Foundation of Health

    46:43 Dopamine: The Devil's Seesaw

    52:41 Hard vs. Soft Dopamine: Resetting the System

    53:28 The Irony of Pleasure and Pain

    55:24 Facing the Elements: Hot and Cold Exposure

    01:01:38 Understanding Emotions and Their Ownership

    01:05:18 Finding Meaning and Purpose in Life

    Resources

    Grant’s latest book – Choose Your Hard

    Available on Amazon

    Website -https://profgrantschofield.com/

    LinkedIn - https://www.linkedin.com/in/grant-schofield-32512728/

    X - https://x.com/grantsnz

    Facebook - https://www.facebook.com/Prof.Grant

    YouTube - https://www.youtube.com/@PREKURE

    Support the Podcast

    If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics.

    See omnystudio.com/listener for privacy information.

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    1 hr and 21 mins
  • Magnesium - the critical roles it plays in your body and how to ensure you're getting enough:Wisdom Wednesdays
    May 5 2026

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    13 mins
  • People Who Get Under Your Skin and What To Do About It With Carly Taylor
    May 3 2026

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    5 mins
  • From Physio to Formula One: Kim Keedle’s Elite Performance Journey
    May 1 2026

    In this episode of the Hardiness Podcast, Kim Keedle shares his fascinating journey from a physiotherapist in Melbourne to a performance coach in the high-octane world of Formula One. Kim discusses his passion for working with athletes, which led him to pursue a master's in strength and conditioning. His career took him to the UK, where he worked with Olympic athletes at the University of Leeds, and eventually into the fast-paced environment of Formula One with the Haas team. Kim reflects on the challenges and rewards of working in elite sports, emphasising the importance of focus, resilience, and continuous improvement.

    Key Takeaways

    • High-performance habits are rooted in simplicity and consistency
    • Elite performance technologies can be accessible and scalable
    • Managing life’s complexity requires mental models that prioritise purpose
    • Reflection and savouring amplify performance and well-being
    • The discipline of visualisation prepares elite minds for unexpected scenarios
    • The sacrifice of the elite is often misunderstood by outsiders
    • Regulating self-talk by requesting honest feedback improves growth

    00:00 Kim Keedle's Journey into Physiotherapy

    02:54 Transition to Strength and Conditioning

    06:00 Experience in Formula One

    09:04 Life on the Road as a Performance Coach

    11:54 Managing Jet Lag and Nutrition

    15:02 Lessons from Elite Sports for Everyday Life

    18:05 Visualisation Techniques for Stress Management

    22:02 Functional Imagery Training and Its Everyday Applications

    24:14 The Transition from Formula One to Personal Life

    26:02 The Pressure of Performance in Sports

    29:56 Lessons from Elite Athletes and Personal Growth

    33:59 The Launch of Pocket Mentor: AI in Coaching

    Resources

    Pocket Mentor: https://pocketmentor.com/

    https://www.linkedin.com/in/kimkeedle/

    https://www.instagram.com/kimkeedle/

    Support the Podcast

    If you found this conversation valuable, consider subscribing and leaving a review on your preferred podcast platform. Your feedback helps us continue to bring you insightful discussions on important health topics.

    See omnystudio.com/listener for privacy information.

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    42 mins
  • Is it true that men and women respond differently to cold water immersion? Wisdom Wednesdays.
    Apr 28 2026

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    18 mins