Early in 2025, BBC Investigations Correspondent Noel Titheradge published his first story about a category of prescription drug with unusual side effects.

People who take dopamine agonist drugs for conditions like Parkinson’s disease or Restless Legs Syndrome often report impulse control disorders - problems with gambling, compulsive eating or shopping, or hypersexuality.

He wasn’t expecting the response. After that first article was published more than 200 people got in touch - that’s me, they said, that’s my partner, that’s my dad.

So Noel started digging.

Details of organisations offering help and support with some of the issues raised are available at bbc.co.uk/actionline.

If you have any concerns about medication you’re taking, speak to your doctor.

Will justice finally prevail? For Shadow World: Stolen Years, the trial of Paul Quinn reaches its verdict. After more than two decades will the victim of the brutal rape finally see the right man convicted?

And at the conclusion of the trial will Andy feel a sense of closure? With two separate investigations still examining the failures in his case, the verdict is not the end of the story.

Shadow World: Gripping stories from the shadows - BBC investigations from across the UK.

Presenter and Producer: Jemma Gander Series Producer and Editor: Fran Robertson Assistant Editor: Christopher Whyte Composer: Sholto Sound design and mix: Chris Maclean Executive Producer for Goldhawk: Kate Holland Commissioning executive: Tracy Williams Commissioning editor: Dan Clarke A Two Step Films production in association with Goldhawk for Radio 4

Why did it take so long to free an innocent man? In Shadow World: Stolen Years, the case against the new suspect in the 2003 rape case gathers pace, while Andrew Malkinson finally receives good news of his own.

But as the series turns to the role of the Criminal Cases Review Commission and the appeal system, a deeper question emerges - how was he left in prison for so long?

Shadow World: Gripping stories from the shadows - BBC investigations from across the UK.

Presenter and Producer: Jemma Gander Series Producer and Editor: Fran Robertson Assistant Editor: Christopher Whyte Composer: Sholto Sound design and mix: Chris Maclean Executive Producer for Goldhawk: Kate Holland Commissioning executive: Tracy Williams Commissioning editor: Dan Clarke

A Two Step Films production in association with Goldhawk for Radio 4

Who is Mr B? In Shadow World: Stolen Years, a DNA match reopens a 20 year old rape case that should have been solved years earlier.

As police investigate the new suspect, Andrew Malkinson begins to reckon with the damage of a wrongful conviction and whether recovery after so many years in prison, is possible. Shadow World: Gripping stories from the shadows - BBC investigations from across the UK.

Presenter and Producer: Jemma Gander Series Producer and Editor: Fran Robertson Assistant Editor: Christopher Whyte Composer: Sholto Sound design and mix: Chris Maclean Executive Producer for Goldhawk: Kate Holland Commissioning executive: Tracy Williams Commissioning editor: Dan Clarke

A Two Step Films production in association with Goldhawk for Radio 4

How can a victim of a traumatic crime appear to be so sure, yet so wrong? In the first episode of Shadow World: Stolen Years we confront the eyewitness evidence that helped convict Andrew Malkinson in 2004.

As a new suspect faces trial over the 2003 rape, Andy meets another woman who made the same devastating mistake, offering him an answer to the question that has haunted him for years. Shadow World: Gripping stories from the shadows - BBC investigations from across the UK.

Presenter and Producer: Jemma Gander Series Producer and Editor: Fran Robertson Assistant Editor: Christopher Whyte Composer: Sholto Sound design and mix: Chris Maclean Executive Producer for Goldhawk: Kate Holland Commissioning executive: Tracy Williams Commissioning editor: Dan Clarke A Two Step Films production in association with Goldhawk for Radio 4

Andrew Malkinson’s wrongful conviction of a brutal rape in 2003 has been recognised as one of the worst miscarriages of justice in UK history. He’s angry and says the criminal justice and appeal systems let him down. Now that the right man has been convicted, he wants answers, and reform. So why did he spend all those years in prison while the perpetrator remained free? And what does his case tell us about the justice system that failed him? In Shadow World: Stolen Years, filmmaker and journalist Jemma Gander (co-director of The Wrong Man: 17 Years Behind Bars) follows the next chapter of this extraordinary case. As Andrew tries to rebuild his life, fresh questions emerge about the role of the police, the courts, and the institutions that failed him. “You don’t know what you’re capable of withstanding until you are forced to. But it’s just horrific”. Twenty three years later, a man is found guilty of the crime Andrew Malkinson was falsely accused of.

Impulse control disorders are a common side effect of dopamine agonist drugs - it’s generally accepted that they will affect around 1 in 6 people taking these drugs for Parkinson’s.

So why are these side effects so hard to talk about? How can people get past their guilt and shame to access the support they need?

And if subtle changes in the activity of chemicals in our brain can cause us to behave so differently - what is personality?

Details of organisations offering help and support with some of the issues raised are available at bbc.co.uk/actionline.

If you have any concerns about medication you’re taking, speak to your doctor.

Presenter: Noel Titheradge Producer: Lucy Burns Editor: Matt Willis A BBC News Long Form Audio production

Respected local solicitor Andrew is sent to prison - but the devastating impact of the side effects of his Parkinson’s medication continues.

BBC Investigations Correspondent Noel Titheradge has been contacted by more than 200 people about their experience of behavioural side effects of dopamine agonist drugs.

So who’s taking responsibility? We hear from pharmaceutical companies, regulators and doctors. There have been significant developments in the way these drugs are used - but what effect have they had?

Details of organisations offering help and support with some of the issues raised are available at bbc.co.uk/actionline.

If you have any concerns about medication you’re taking, speak to your doctor.

Presenter: Noel Titheradge Producer: Lucy Burns Editor: Matt Willis A BBC News Long Form Audio production