What really happens to your skin after major weight loss on GLP-1 medications, and when does surgery make sense? In this episode, Ana talks with Dr. Maryam Zamani, a double board-certified plastic surgeon, about why loose skin happens, how GLP-1-related skin changes may differ from traditional weight loss, and what people can do before jumping into surgery. They also cover the real role of protein and muscle mass, the limits of non-surgical treatments, and the most common surgical options for the face, breasts, arms, abdomen, thighs, and back after significant weight loss.

About Dr. Maryam Zamani:
Dr. Maryam Zamani is a dual board-certified plastic surgeon specializing in refined, natural-looking facial, breast, and body procedures, with particular expertise in helping patients navigate the physical changes that follow significant weight loss, including GLP-1 use. Certified in both the U.S. and Canada, fellowship-trained in aesthetic surgery, and an editorial board member for The Aesthetic Surgery Journal, she combines advanced surgical and non-surgical treatments to address loose skin, facial volume loss, breast changes, and body contouring with an elegant, highly individualized approach.

Guest Links:

• Plastic Surgery In Beverly Hills | Cosmetic Surgery In Los Angeles
• www.instagram.com/dr.maryamzamani

Episode Sponsor

Brello: A GLP-1 telehealth platform connecting you with licensed providers. Visit http://brello.com to learn more.

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YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

If GLP-1 medications have quieted your food noise but left you wondering how to handle the emotions underneath it, this episode is for you. Ana talks with Jessica Brown about why weight loss alone does not automatically heal your relationship with food, how self-compassion can help you move out of shame and self-sabotage, and what it looks like to work on identity, coping patterns, and emotional resilience while using GLP-1 medications. This conversation connects the physical effects of medication with the inner work that helps change actually last.

About Jessica Brown:
Jessica Brown is a clinical nutritionist, Stanford-certified compassion teacher, and author of Beyond the Shot: Inner Work for Lasting Success on Weight Loss Medications. She is the founder of Nourishful Inc., publishing under Inner Well Press, and the creator of the GLP-1 Nutrition Academy. With nearly 25 years of experience, Jessica specializes in helping people navigate the emotional and psychological side of GLP-1 use, including food cravings, binge eating, self-compassion, reparenting, and body image healing. Her work blends evidence-based nutrition with compassionate, therapeutic approaches that support lasting transformation beyond temporary weight loss.

Guest Links:

• The Loving Diet™
• Self-Compassion Teacher & Clinical Nutritionist — The Loving Diet™
• Emotional Eating Signals And Solutions — The Loving Diet™
• Jessica Brown (@thelovingdiet) • Instagram profile
• https://www.linkedin.com/in/thelovingdiet/

Episode Sponsors:

Brello: A GLP-1 telehealth platform connecting you with licensed providers. Visit http://brello.com to learn more.

Harvest Snaps by Calbee America and enter SNAPS15 at checkout for 15% off your order, now through June 30.

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

What does long-term GLP-1 use actually look like in real life?

In this episode, Ana sits down with clinical pharmacist Kimmi Le of Solara Labs/Barimelts to talk about the bigger picture of staying on GLP-1 medications over time. They unpack why weight loss alone is not the same thing as better health, what labs and biomarkers matter most, and how to think about muscle, nutrient status, digestion, inflammation, and long-term maintenance. Kimmi shares a practical perspective on microdosing, why some patients may do better staying on a lower long-term dose, and how to avoid the cycle of losing and regaining weight. They also talk about nutrient absorption, supplement quality, bariatric surgery considerations, and what may be coming next in the GLP-1 space.

In this episode, you’ll learn:

• Why “the scale going down” doesn’t always mean health is improving
• The role of exercise and muscle preservation on GLP-1s
• How slowed digestion can affect nutrient absorption
• What bariatric patients should keep in mind when using GLP-1 medications
• Why form and quality matter when choosing supplements
• How clinicians are thinking about long-term use, lower dosing, and maintenance

About Kimmi Le: Kimmi Le is a clinical pharmacist with additional training in nutrition, herbalism, and culinary medicine through Tulane Medical School’s teaching kitchen. She works in the supplement space with Solara Labs/Barimelts, with a focus on practical support for women using GLP-1 medications and bariatric patients.

Episode Sponsors:

Barimelts: https://www.barimelts.com/

Brello: A GLP-1 telehealth platform connecting you with licensed providers. Visit http://brello.com to learn more.

Timeline Mitopure: Go to timeline.com/glp1hub for up to 20% off.

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

Jess Perreca joins Ana Reisdorf to share his powerful personal story of obesity, massive weight loss, regain, bariatric surgery, and what finally feels different in this season of his life with GLP-1 support. He opens up about growing up with obesity, reaching nearly 600 pounds, losing more than 200 pounds twice, and the emotional patterns that kept pulling him backward. Jess also explains why one of the biggest changes hasn’t just been the weight loss itself, but the relief from pain, inflammation, and swelling that has made everyday life feel more manageable. This is an honest conversation about food noise, emotional eating, shame, persistence, and what it looks like to keep going even after setbacks.

About Our Guest

Jess Perreca Jr. is the creator of Time4Change365 and Everyday Ascend, where he shares an honest look at weight loss, mindset, and what sustainable change really takes. After reaching a high of 588 pounds, Jess lost well over 200 pounds, experienced regain, and recommitted to his health with structure, accountability, and transparency. His journey has included bariatric surgery, GLP-1 medication, and the ongoing mental battle with food noise, shame, and consistency that so many people living with obesity understand firsthand. A husband, father of two, and full-time IT professional, Jess now uses his platforms to encourage others to keep moving forward and become 1% better each day.

Guest Links

Instagram: @time4change365

Instagram: @everydayascendco

Website: everydayascend.com

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

If you're on a GLP-1 and trying to eat well when your appetite is low, this episode is full of practical, realistic advice. Ana sits down with Cassandra Lepore, known online as @dietitianCass, to break down what smarter snacking actually looks like on a GLP-1. They also dig into what Cassandra is seeing inside the food industry as brands adapt products and messaging for GLP-1 users.

Ana also closes the episode by answering a listener question about GLP-1-related hair loss, including what may cause it, what emerging research is suggesting, and what steps may help right now.

About Our Guest:

Cassandra Lepore is a dietitian and social media nutrition educator known online as @dietitianCass. She works full-time behind the scenes with CPG food and beverage brands, including work focused on how products can better support people using GLP-1 medications. Her work centers on translating evidence-based nutrition into practical, easy-to-understand advice.

Connect with Cassandra Lepore

Instagram: @dietitianCass
TikTok: @dietitianCass
LinkedIn: Cassandra Lepore

Resources mentioned

GLP-1 Hair Loss Cheat Sheet: https://join.glp-1hub.com/hairloss
GLP-1 Hub hair loss YouTube Links:

Fixing Hair Loss on a GLP-1: https://youtu.be/06M5ZU9j-Ww

Hair Loss New Study Update: https://youtu.be/OjFQn6gDreY

Episode Sponsors:

Harvest Snaps — 5g protein and 4g fiber per serving. Use code SNAP15 at HarvestSnaps.com for 15% off through June 30.

Barimelts — Use code GLP1HUB at Barimelts.com for 25% off.

Timeline Mitopure — Go to timeline.com/glp1hub for up to 20% off.

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

If you’ve noticed your pain improving on a GLP-1 medication, you may not be imagining it, and it may not be just because of weight loss. In this episode, Ana sits down with Dr. Asare Christian, an integrative pain management physician, to talk about why chronic pain is often treated too narrowly, how inflammation, sleep, trauma, stress, and metabolic health all shape the pain experience, and why GLP-1 medications like semaglutide may have a direct pain-relieving effect even at low doses. They also dig into migraines, how low-dose semaglutide may fit into pain care, the micronutrients that still matter when appetite is lower, and why lasting pain relief usually takes more than a single medication or procedure.

About our Guest:
Dr. Asare B. Christian, MD, MPH, FAAMFM, is a board-certified longevity medicine physician and founder of Aether Medicine, a concierge performance & longevity clinic in Pennsylvania. Trained at Johns Hopkins and Harvard, he specializes in solving pain, optimizing hormones and metabolism, and advancing healthspan through precision diagnostics and evidence-based cellular therapies. He combines rigorous science with innovative medicine to help patients improve performance, resilience, and long-term vitality.

Connect with Dr. Christian
Website: Aether Medicine - Integrative Pain Management Specialist - Wayne, PA

Episode Sponsors:

Metagenics: Explore our complete collection of science-backed supplements.

Harvest Snaps: Harvest Snaps by Calbee America Enter SNAPS15 at checkout for 15% off your order, now through June 30.

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

If your GLP-1 has quieted more than food noise, this episode will help you understand why. Ana sits down with Dr. Steven Klein, addiction medicine physician at Caron Treatment Centers, PhD in human genetics, person in long-term recovery, and long-term GLP-1 user, to unpack how GLP-1 medications may reduce cravings beyond food.

In this episode, you'll learn:

• Why food noise and addiction cravings can come from the same brain circuitry
• How GLP-1s may reduce alcohol, opioid, and other compulsive urges
• Whether these medications blunt pleasure or simply reduce obsession
• Why low-dose treatment may still help with cravings
• What habits, support, and recovery tools still matter on or off medication
• How genetics, epigenetics, and chronic stress may influence addiction risk
• Where someone can start if they need help for addiction

About our Guest Dr. Steven Klein:
Dr. Steven Klein is a physician-scientist specializing in addiction medicine with expertise in pediatrics, medical genetics, and the neurobiology of substance use.
At Caron, he plays a leading role in advancing biologically informed therapies for recovery, including the integration of GLP-1 receptor agonists to reduce cravings and support long-term outcomes. Dr. Klein earned both his MD and PhD in Human Genetics through UCLA’s Medical Scientist Training Program and completed residency and postdoctoral research at the Children’s Hospital of Philadelphia. He is board-certified in pediatrics and addiction medicine and board-eligible in medical genetics.

You can connect with Dr. Klein and Caron here.

Episode Sponsors:

Timeline / Mitopure: Mitopure® | #1 Doctor Recommended Urolithin A

Harvest Snaps: Harvest Snaps by Calbee America and enter SNAPS15 at checkout for 15% off your order, now through June 30.

Barimelts: Go to Barimelts.com and use code GLP1HUB for 25% off your order

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.

GLP-1 medications can be life-changing, but rapid weight loss can also mean losing muscle if you are not actively protecting it. In this episode, Ana Reisdorf sits down with registered dietitian Jennifer Scheinman to talk about why muscle strength matters just as much as muscle mass, how mitochondria influence energy, mobility, and healthy aging, and what GLP-1 users can do right now to support muscle with a balanced diet, enough protein, exercise, and smart supplementation. They also break down the emerging research on urolithin A, including how it may support mitochondrial recycling and muscle strength, why that matters for fatigue and long-term function, and where it may fit into a practical GLP-1 lifestyle.

About Our Guest:

Jennifer Scheinman is a registered dietitian with about 25 years of experience across clinical practice, private practice, and the wellness space. She currently works as the Director of Scientific Communications with Timeline, where she focuses on evidence-based supplement education and longevity research.

Timeline Instagram: (@timelinelongevity) • Instagram profile
Jen Instagram: Jen Scheinman | Perimenopause Dietitian Nutritionist (@jenscheinman_nutrition) • Instagram profile

Episode Sponsors:

Timeline / Mitopure: Mitopure® | #1 Doctor Recommended Urolithin A

Metagenics: Explore our complete collection of science-backed supplements.

I Can't Believe it's not Butter!: See how NutriRich “I can’t Believe it’s not Butter!” can help on your GLP-1 Journey at the ICBINB Wellness Hub

Want to Learn More about GLP-1 Hub?

Join the Steady State newsletter and get a FREE 7-day meal plan + weekly support and strategy to optimize your journey:

http://join.glp-1hub.com

Join the membership:

https://glp-1hub.com/membership

Visit our GLP-1 Hub store:

https://shop.glp-1hub.com

Want to connect more with GLP-1 Hub?

Instagram: https://www.instagram.com/glp1hub

Tiktok: https://www.tiktok.com/@glp1hub

YouTube: https://www.youtube.com/@glp-1hub

*Some of the links shared are affiliate links. When you make a purchase, I will receive a small commission at no cost to you. Thank you for supporting the show.

*The content of this show is for informational purposes only and does not constitute medical advice. The goal of this show is to provide various points of view about GLP-1 Medications. The personal and professional opinion of the guests and their content does not necessarily reflect the opinion of Ana Reisdorf or GLP-1 Hub.