Peter Boghossian presses Dr. Drew on the treatments medicine won't touch, including ibogaine for opioid addiction, peptides, GLP-1 risks, and hormone replacement therapy. Dr. Drew doesn't hedge. What emerges is an argument for evidence-based medicine in an era of regulatory timidity, and with Trump's executive order on psychedelics, that conversation just became more urgent. The discussion ends where it should, not with longevity hacks, but with the question of what makes a life worth living.

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I engage Physician and author Aaron Stupple on whether children deserve full sovereignty, and why the answer exposes a contradiction in how we raise our kids.

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Craig Biddle makes the case that Objectivism is not simply Ayn Rand's philosophy but the only philosophically defensible foundation for individual rights, reason, and a free society. Peter Boghossian pushes back, probing the epistemological claims, the treatment of altruism, and whether a closed system can survive genuine philosophical scrutiny.

What emerges is a collision between a defender of a complete moral framework and a skeptic who refuses to let any idea off the hook. If you think philosophy is abstract, this conversation will change your mind.

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