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Biohacking Eve - Health Optimisation for Women

Biohacking Eve - Health Optimisation for Women

By: Judith Mueller
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Biohacking Eve - differentiated health optimisation for women. Let's make it all about Eve!

Have you ever listened to the titans of Health Optimisation, Biohacking and Longevity and wondered “That’s all really great, but what if I’m a woman?”

If so, welcome to “Biohacking Eve – Health Optimisation for Women!”

My name is Judith Mueller and I’m here to help you navigate the maze of information by shining a light on true differentiation for women when it comes to health optimisation.

Together, we will explore everything from how to fast intermittently without ruining your hormones all the way to abolishing menopause, and I will show you the latest in technology and research that can help you address your individual struggles and challenges in becoming your best self as a woman, as unique and individual as only you can be.

Live long and prosper, my friend.

© 2026 Biohacking Eve - Health Optimisation for Women
Hygiene & Healthy Living
Episodes
  • #21 Pt1: Ocean Wave, Avalanche or Volcano? 40 Years of Female Orgasm Science
    Jul 7 2026
    Send us Fan MailAnna Lee, CEO and co-founder of Lioness, joins Judith to reveal what a dataset of around 100,000 orgasms has uncovered about female sexual pleasure — and how little the science had actually established before. This part covers how the Lioness biofeedback vibrator measures involuntary pelvic-floor contractions, the three distinct orgasm patterns the data reveals, and the finding that will genuinely surprise most listeners: orgasm strength tends to increase as women move into their fifties and sixties, not decline.Key topics discussed- What the Lioness device actually measures, and how biofeedback orgasm data works- The three orgasm patterns — ocean wave (rhythmic, most common), avalanche (high force tapering down), and volcano (rare, single explosive peak) — identified through involuntary pelvic-floor contractions- Why those patterns matter: correcting four decades of incomplete research based on a 1982 study of only 11 women- The type-switching debate: whether a person moves between orgasm patterns over time, and what the current data does and does not show- The age finding: women aged 51–60 appear to reach orgasm fastest and generate the strongest peak force — contradicting the widespread assumption that sexual pleasure declines with age- Why this podcast cares: the knowledge gap in female sexual health, and how understanding your own body is a health act, not a vanity oneTimestampsThese are estimates and may shift in final editing.0:00 — Introduction: Judith introduces Anna Lee and Lioness1:00 — What Lioness measures: involuntary pelvic-floor contractions during pleasure and orgasm2:30 — How the app works: pairing the device, reading the data, tracking lifestyle factors4:00 — The three orgasm patterns: ocean wave, avalanche, volcano6:30 — The 1982 Bohlen study (n=11) versus the Lioness dataset (~100,000 data points); the Pfaus/Hartmann research8:30 — The type-switching debate: do people move between patterns?10:00 — The age study: orgasm strength increases in the 51–60 range12:30 — Why this matters: "knowledge is pleasure," and the parallel to tracking sleep and nutrition14:00 — Fertility and orgasm type: what we do and do not know15:30 — End of Part 1ReferencesLioness Smart VibratorThe biofeedback device discussed throughout. Measures involuntary pelvic-floor contractions during pleasure and orgasm and displays the data via paired smartphone app.https://lioness.ioPfaus J, Hartmann D, Wood E, Wang J, Klinger E. "Women's Orgasms Determined by Autodetection of Pelvic Floor Muscle Contractions Using the Lioness 'Smart' Vibrator."The Journal of Sexual Medicine, 2022, Vol 19, Suppl 3. Led by Dr. Jim Pfaus of Charles University, Prague. The study defining the three orgasm patterns (ocean wave, avalanche, volcano) using the Lioness dataset; approximately 37–40 participants.https://academic.oup.com/jsm/article-abstract/19/Supplement_3/S2/7012773Hartmann D, Pfaus J, Wood E, Klinger L, Wang J. "Are All Orgasms Created Equally Regardless of Age?"The Journal of Sexual Medicine, 2023, Vol 20, Suppl 2. Led by Dee Hartmann, pelvic-floor therapist. Study of 26 women aged 21–60 showing that women aged 51–60 reached orgasm fastest and generated the strongest peak force (~1,425 gm/f).https://academic.oup.com/jsm/article/20/Supplement_2/qdad061.034/7165577Bohlen JG et al. "The Female Orgasm: Pelvic Contractions."Archives of Sexual Behavior, 1982. The original study identifying different orgasm contraction patterns in 11 women. The foundational paper that the Lioness research builds on and substantially extends.[No URL — print publication; flag for editorial review if a DOI link is required]Dr. Jim PfausResearcher at Charles University, Prague. Led the orgasm-pattern classification study using Lioness data.Dee HartmannPelvic-floor therapist based in the United States. Led the age and orgasm-strength study using Lioness data. Also mentioned in connection with the Kegel/pelvic-floor research (covered in Part 2).Guest links and socialsAnna Lee, CEO and co-founder of LionessLioness website: https://lioness.ioLioness Instagram: @lionesshealthLioness LinkedIn: https://www.linkedin.com/company/lionesshealthAnna Lee personal Instagram: @annaisaverageAnna Lee personal LinkedIn: https://www.linkedin.com/in/annakleeLioness app: available on iOS and Android — search 'Lioness' in the App Store or Google PlayInsta/TikTok: @BiohackingEveWebsite: www.BiohackingEve.com
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    15 mins
  • #20 Pt3: Could Endometriosis Be a Microbiome Disease?
    Jun 23 2026

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    In Part 3, Ronny Szelinsky moves into the frontier: AI-based endometrial diagnostics, the seeding event that shapes your baby's immune system at birth, the emerging theory that endometriosis may be a microbiome disease, and a clinical prediction for where gynaecological medicine is heading over the next decade. The episode closes with the curveball section, including book recommendations and perspectives on the gender health gap.

    Key Topics
    Seeding: how the birth canal colonises the newborn with foundational bacteria, and what C-section babies miss
    How to manually replicate seeding — and why most hospitals don't
    Why each successive birth reduces the mother's microbiome diversity
    AI diagnostics: inferring endometrial microbiome state from a vaginal swab (no biopsy)
    Applications for fertility clinics; pre-IVF screening; personalised probiotic protocols
    What is scientifically established vs currently speculative in the gynecological microbiome field
    Endometriosis as a potential endpoint of chronic microbiome dysfunction: the emerging theory
    Antimicrobial resistance and gynecological probiotics
    Why antibiotics sometimes trigger irregular bleeding — and the microbiome explanation
    Clinical prediction: microbiome assessment as routine gynaecological practice within ten years
    Curveball: recommended books, electrolytes, Rwanda project, ideal sidekick

    Timestamps
    [Part 3 start] — Seeding: the birth canal microbiome transfer
    [~05:00 into part] — C-section, missed seeding, manual replication
    [~08:00] — Why microbiome diversity declines with each birth
    [~10:00] — AI diagnostics: vaginal swab inference for endometrial state
    [~16:00] — Fertility clinic use cases; personalised probiotic prescribing
    [~20:00] — What is established vs speculative in the field
    [~23:00] — Endometriosis and the microbiome theory
    [~27:00] — Antibiotics, irregular bleeding, antimicrobial resistance
    [~30:00] — Ten-year clinical prediction
    [~33:00] — Curveball questions

    References and Resources
    Get Happy website: www.get-happy.com
    Ronny Szelinsky — LinkedIn: https://www.linkedin.com/in/ronny-szelinsky
    Darm mit Charme by Jill Enders (English: Gut — The Inside Story of Our Body’s Most Underrated Organ)
    Herzenssache by Prof. Michael Becker (not available in English) — book on the female heart and gender differences in cardiovascular medicine
    Boundless by Ben Greenfield — longevity and biohacking reference book; both Ronny and Judith recommend.


    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    43 mins
  • #20 Pt2: How the Pill Disrupts the Microbiome Long-Term
    Jun 9 2026

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    In Part 2, Ronny Szelinsky explains the mechanism behind oestrogen-driven microbiome collapse at menopause — and what can be done about it. He introduces the estrobolome, details the research behind Get Happy's Happy Fem probiotic formula, and explains why oral probiotics colonise the gynecological tract as effectively as vaginal delivery. This is the translational bridge between the science of Part 1 and the practical interventions of Part 3.



    Key Topics

    • How oestrogen controls the thickness of the vaginal and endometrial tissue, and what happens when it drops
    • Why UTIs become suddenly frequent after menopause — the biological mechanism
    • Vaginal dryness and pain during sex: the mucosal layer explained
    • The estrobolome: the bacterial community around the ovaries and its proposed role in oestrogen production
    • The contraceptive pill and its long-term impact on microbiome colonisation after stopping
    • Happy Fem: how the product was developed, the research methodology, and the fertility clinic partnerships
    • Why oral probiotics achieve equivalent vaginal colonisation to vaginal administration — three pathways
    • Lactobacillus CA-15: what the published research shows
    • Who should take vaginal probiotics and under what circumstances
    • When to pause: during pregnancy, and why
    • Dosing: six-month courses for specific goals; ongoing daily use for post-menopausal women



    Timestamps

    • [Part 2 start] — Hormone-microbiome axis, oestrogen and tissue thickness
    • [~05:00 into part] — Why UTIs spike at menopause
    • [~10:00] — The estrobolome: ovarian bacteria and oestrogen production
    • [~17:00] — Happy Fem: product development and research methodology
    • [~22:00] — Oral vs vaginal administration — clinical study results
    • [~27:00] — Lactobacillus CA-15: what it does
    • [~30:00] — Who should take it; when to pause; dosing logic



    References and Resources

    • Happy Fem product: www.get-happy.com
    • Lactobacillus CA-15

    Insta/TikTok: @BiohackingEve
    Website: www.BiohackingEve.com

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    36 mins
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