Psychedelics Can Rewrite the DNA of Trauma
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Last Friday, President Trump signed an executive order directing the FDA to fast-track psychedelic medicines for mental health treatment. Joe Rogan texted him about Ibogaine. The president texted back. Fifty million federal dollars followed.
You can have a lot of feelings about how that happened.
Here is what is not political: a small group of neuroscientists and psychiatrists spent the last decade quietly building the scientific case that certain psychedelic compounds can do something no pill or therapy has ever done. Dr. David Rabin is one of them. He has been training clinicians, treating veterans with PTSD that responded to nothing, and running what has been called the largest controlled study of psychedelic medicines in the world. He published a paper in 2023 showing that MDMA assisted therapy produces measurable changes in the DNA of PTSD patients, at the level of the cortisol receptor, in direct proportion to how much better they got.
Washington just showed up to a party that started ten years ago.
Dr. Kevin White sits down with Dr. Rabin to talk about what MDMA is actually doing in the brain, why the safety hypothesis changes how you think about stress and chronic illness, what Ibogaine does to opioid receptors that nothing else can, and why most of the ketamine being prescribed right now is being given wrong.
"Psychedelic medicines are to mental illness what antibiotics were to infection in the first half of the 20th century."
The science was already there. Now find out what it actually says.
Find more from Dr. Rabin at drdave.io and apolloneuro.com. Try the Apollo wearable at wearablehugs.com. His first book, A Simple Guide To Being Alive, is available at asimpleguidetobeingalive.com
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